| IL33 |
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| Наявні структури |
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| PDB | Пошук ортологів: PDBe RCSB |
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| Список кодів PDB | | 2KLL, 4KC3 | | |
| Ідентифікатори |
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| Символи | IL33, C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV, Interleukin 33, IL-33, IL-1F11 |
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| Зовнішні ІД | OMIM: 608678 MGI: 1924375 HomoloGene: 14126 GeneCards: IL33 |
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| Пов'язані генетичні захворювання |
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| бронхіальна астма, ендометріоз[1] |
| Онтологія гена |
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| Молекулярна функція | • cytokine activity
• GO:0001948, GO:0016582 protein binding
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| Клітинна компонента | • transport vesicle
• хромосома
• GO:0016023 cytoplasmic vesicle
• клітинне ядро
• extracellular region
• міжклітинний простір
• нуклеоплазма
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| Біологічний процес | • negative regulation of interferon-gamma production
• positive regulation of inflammatory response
• positive regulation of interleukin-5 production
• extrinsic apoptotic signaling pathway
• positive regulation of macrophage activation
• negative regulation of T-helper 1 type immune response
• positive regulation of interleukin-4 production
• transcription, DNA-templated
• positive regulation of interleukin-13 production
• GO:1901313 positive regulation of gene expression
• defense response to virus
• positive regulation of interleukin-6 production
• positive regulation of type 2 immune response
• negative regulation of leukocyte migration
• positive regulation of proteasomal ubiquitin-dependent protein catabolic process
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• microglial cell proliferation
• macrophage activation involved in immune response
• microglial cell activation involved in immune response
• type 2 immune response
• protein deubiquitination
• regulation of signaling receptor activity
• interleukin-33-mediated signaling pathway
• positive regulation of neuroinflammatory response
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| Джерела:Amigo / QuickGO | |
| Ортологи |
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| Види | Людина | Миша |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (мРНК) | NM_001199640
NM_001199641
NM_001314044
NM_001314045
NM_001314046
| NM_001314047
NM_001314048
NM_033439
NM_001353802 |
| | NM_001164724
NM_133775
NM_001360725 |
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| RefSeq (білок) | NP_001186569
NP_001186570
NP_001300973
NP_001300974
NP_001300975
| NP_001300976
NP_001300977
NP_254274
NP_001340731 |
| | NP_001158196
NP_598536
NP_001347654 |
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| Локус (UCSC) | Хр. 9: 6.22 – 6.26 Mb | Хр. 19: 29.9 – 29.94 Mb |
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| PubMed search | [2] | [3] |
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| Вікідані |
| Див./Ред. для людей | Див./Ред. для мишей |
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