ZYG11B

Protein-coding gene in the species Homo sapiens
ZYG11B
Identifiers
AliasesZYG11B, ZYG11, zyg-11 family member B, cell cycle regulator
External IDsMGI: 2685277; HomoloGene: 14600; GeneCards: ZYG11B; OMA:ZYG11B - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for ZYG11B
Genomic location for ZYG11B
Band1p32.3Start52,726,453 bp[1]
End52,827,336 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for ZYG11B
Genomic location for ZYG11B
Band4|4 C7Start108,086,921 bp[2]
End108,158,293 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • deltoid muscle

  • vastus lateralis muscle

  • tibialis anterior muscle

  • biceps brachii

  • Skeletal muscle tissue of biceps brachii

  • Skeletal muscle tissue of rectus abdominis

  • cardiac muscle tissue of right atrium

  • myocardium of left ventricle

  • right ventricle

  • middle temporal gyrus
Top expressed in
  • medial vestibular nucleus

  • medial dorsal nucleus

  • mammillary body

  • lateral hypothalamus

  • ventral tegmental area

  • lateral geniculate nucleus

  • dorsal tegmental nucleus

  • medial geniculate nucleus

  • ventromedial nucleus

  • dorsomedial hypothalamic nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • ubiquitin-protein transferase activity
Cellular component
  • Cul2-RING ubiquitin ligase complex
Biological process
  • regulation of ubiquitin-protein transferase activity
  • protein ubiquitination
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79699

414872

Ensembl

ENSG00000162378

ENSMUSG00000034636

UniProt

Q9C0D3

Q3UFS0

RefSeq (mRNA)

NM_024646

NM_001033634

RefSeq (protein)

NP_078922

NP_001028806

Location (UCSC)Chr 1: 52.73 – 52.83 MbChr 4: 108.09 – 108.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zyg-11 family member B, cell cycle regulator is a protein that in humans is encoded by the ZYG11B gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162378 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034636 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zyg-11 family member B, cell cycle regulator".

Further reading

  • Vasudevan S, Starostina NG, Kipreos ET (March 2007). "The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components". EMBO Reports. 8 (3): 279–86. doi:10.1038/sj.embor.7400895. PMC 1808032. PMID 17304241.
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