ZNF436

Protein-coding gene in the species Homo sapiens
ZNF436
Identifiers
AliasesZNF436, ZNF, Zfp46, zinc finger protein 436
External IDsOMIM: 611703; MGI: 99192; HomoloGene: 40684; GeneCards: ZNF436; OMA:ZNF436 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for ZNF436
Genomic location for ZNF436
Band1p36.12Start23,359,448 bp[1]
End23,369,836 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for ZNF436
Genomic location for ZNF436
Band4 D3|4 68.34 cMStart136,011,994 bp[2]
End136,021,253 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • endometrium

  • Achilles tendon

  • corpus callosum

  • ganglionic eminence

  • right adrenal gland

  • smooth muscle tissue

  • mucosa of esophagus

  • left adrenal gland

  • gallbladder

  • ovary
Top expressed in
  • vas deferens

  • tunica media of zone of aorta

  • Rostral migratory stream

  • ciliary body

  • calvaria

  • efferent ductule

  • olfactory tubercle

  • iris

  • abdominal wall

  • tunica adventitia of aorta
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • protein binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
  • nucleoplasm
  • cytosol
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

80818

22704

Ensembl

ENSG00000125945
ENSG00000283009

ENSMUSG00000051351

UniProt

Q9C0F3

Q8BPP0

RefSeq (mRNA)

NM_001077195
NM_030634
NM_001370652

NM_009557
NM_001356308
NM_001370651

RefSeq (protein)

NP_001070663
NP_085137
NP_001357581

NP_033583
NP_001343237
NP_001357580

Location (UCSC)Chr 1: 23.36 – 23.37 MbChr 4: 136.01 – 136.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 436 is a protein that in humans is encoded by the ZNF436 gene.[5][6]

See also

References

  1. ^ a b c ENSG00000283009 GRCh38: Ensembl release 89: ENSG00000125945, ENSG00000283009 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051351 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
  6. ^ "Entrez Gene: ZNF436 zinc finger protein 436".

Further reading

  • Li Y, Du X, Li F, et al. (2007). "A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE". Mol. Biol. Rep. 33 (4): 287–94. doi:10.1007/s11033-006-9019-5. PMID 17089209. S2CID 13591444.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
  • Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.


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