RTF1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2BZE, 2DB9, 3U1U, 4L1P, 4L1U |
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Identifiers |
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Aliases | 15890 RTF1, RTF2, GTL7, KIAA0252, RTF1 homolog, Paf1/RNA polymerase II complex component, RTF2, C20orf43, CDAO5, HSPC164, SHUJUN-3, replication termination factor 2 domain containing 1, replication termination factor 2, RTFDC1 |
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External IDs | OMIM: 611633; MGI: 1309480; HomoloGene: 133868 9501; GeneCards: RTF2 RTF1, RTF2; OMA:RTF1, RTF2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 15 (human)[1] |
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| Band | 15q15.1, 20q13.31 | Start | 41,408,408 bp[1] |
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End | 41,483,563 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 E5 | Start | 119,675,068 bp[2] |
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End | 119,735,407 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ganglionic eminence
- Skeletal muscle tissue of rectus abdominis
- palpebral conjunctiva
- epithelium of colon
- ventricular zone
- bone marrow cells
- cerebellar hemisphere
- Skeletal muscle tissue of biceps brachii
- body of tongue
- monocyte
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| Top expressed in | - tail of embryo
- zygote
- genital tubercle
- hand
- yolk sac
- superior cervical ganglion
- foot
- interventricular septum
- primitive streak
- fossa
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| More reference expression data |
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BioGPS | | 51507/ More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- single-stranded DNA binding
- DNA binding
- RNA polymerase II C-terminal domain phosphoserine binding
- RNA binding
- molecular function
| Cellular component | - nucleolus
- nucleus
- Cdc73/Paf1 complex
- nucleoplasm
- cellular component
- replication fork
- chromosome
| Biological process | - blastocyst growth
- histone modification
- regulation of transcription, DNA-templated
- positive regulation of transcription elongation from RNA polymerase II promoter
- histone H3-K4 trimethylation
- positive regulation of histone H3-K4 methylation
- transcription, DNA-templated
- Wnt signaling pathway
- positive regulation of transcription by RNA polymerase II
- negative regulation of transcription by RNA polymerase II
- stem cell population maintenance
- endodermal cell fate commitment
- transcription by RNA polymerase II
- transcription elongation from RNA polymerase II promoter
- protein ubiquitination
- mitotic DNA replication termination
- site-specific DNA replication termination at RTS1 barrier
- biological process
- cellular response to hydroxyurea
- regulation of DNA stability
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000137815 ENSG00000022277 |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_015138 NM_001283035 NM_001283036 NM_001283037 NM_016407 |
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RefSeq (protein) | |
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NP_055953 NP_001269964 NP_001269965 NP_001269966 NP_057491 |
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Location (UCSC) | Chr 15: 41.41 – 41.48 Mb | Chr 2: 119.68 – 119.74 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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