RNF34 |
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Identifiers |
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Aliases | RNF34, CARP-1, CARP1, RFI, RIF, RIFF, hRFI, ring finger protein 34 |
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External IDs | OMIM: 608299; MGI: 2153340; HomoloGene: 11839; GeneCards: RNF34; OMA:RNF34 - orthologs |
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Gene location (Human) |
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![Chromosome 12 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Ideogram_human_chromosome_12.svg/300px-Ideogram_human_chromosome_12.svg.png) | Chr. | Chromosome 12 (human)[1] |
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| Band | 12q24.31 | Start | 121,400,083 bp[1] |
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End | 121,430,623 bp[1] |
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Gene location (Mouse) |
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![Chromosome 5 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_5.svg/260px-Ideogram_house_mouse_chromosome_5.svg.png) | Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5|5 F | Start | 122,988,111 bp[2] |
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End | 123,009,354 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - secondary oocyte
- Skeletal muscle tissue of rectus abdominis
- Skeletal muscle tissue of biceps brachii
- triceps brachii muscle
- glutes
- ganglionic eminence
- muscle of thigh
- gonad
- middle temporal gyrus
- Brodmann area 23
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| Top expressed in | - zygote
- secondary oocyte
- primary oocyte
- tail of embryo
- right ventricle
- medial ganglionic eminence
- genital tubercle
- spermatid
- granulocyte
- temporal muscle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/c/c8/PBB_GE_RNF34_219035_s_at_fs.png/250px-PBB_GE_RNF34_219035_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - metal ion binding
- phosphatidylinositol phosphate binding
- p53 binding
- ubiquitin protein ligase binding
- protein binding
- ubiquitin protein ligase activity
- ubiquitin-protein transferase activity
- transferase activity
| Cellular component | - cytoplasm
- endomembrane system
- nucleus
- membrane
- plasma membrane
- nuclear speck
- nucleoplasm
- cytosol
- nuclear body
| Biological process | - negative regulation of signal transduction by p53 class mediator
- negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
- nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
- protein K48-linked ubiquitination
- negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
- apoptotic process
- regulation of oxygen metabolic process
- cellular response to cold
- protein ubiquitination
- proteasome-mediated ubiquitin-dependent protein catabolic process
- ubiquitin-dependent protein catabolic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_194271 NM_001256858 NM_025126 NM_001394208 |
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RefSeq (protein) | |
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NP_001243787 NP_079402 NP_919247 |
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Location (UCSC) | Chr 12: 121.4 – 121.43 Mb | Chr 5: 122.99 – 123.01 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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