PLXDC2

Protein-coding gene in the species Homo sapiens
PLXDC2
Identifiers
AliasesPLXDC2, TEM7R, plexin domain containing 2
External IDsOMIM: 606827; MGI: 1914698; HomoloGene: 41666; GeneCards: PLXDC2; OMA:PLXDC2 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for PLXDC2
Genomic location for PLXDC2
Band10p12.31Start19,816,239 bp[1]
End20,289,856 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for PLXDC2
Genomic location for PLXDC2
Band2|2 A2- A3Start16,361,115 bp[2]
End16,760,650 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • tendon of biceps brachii

  • saphenous vein

  • synovial joint

  • skin of hip

  • monocyte

  • lower lobe of lung

  • Descending thoracic aorta

  • hair follicle

  • lactiferous duct
Top expressed in
  • vestibular membrane of cochlear duct

  • ankle

  • belly cord

  • epithelium of lens

  • esophagus

  • ascending aorta

  • right kidney

  • aortic valve

  • skin of external ear

  • lip
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

84898

67448

Ensembl

ENSG00000120594

ENSMUSG00000026748

UniProt

Q6UX71

Q9DC11

RefSeq (mRNA)

NM_001282736
NM_032812

NM_026162

RefSeq (protein)

NP_001269665
NP_116201

NP_080438

Location (UCSC)Chr 10: 19.82 – 20.29 MbChr 2: 16.36 – 16.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Plexin domain-containing protein 2 is a protein that in humans is encoded by the PLXDC2 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120594 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026748 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B (Sep 2001). "Cell surface tumor endothelial markers are conserved in mice and humans". Cancer Res. 61 (18): 6649–55. PMID 11559528.
  6. ^ "Entrez Gene: PLXDC2 plexin domain containing 2".

Further reading

  • Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.
  • Nanda A, Buckhaults P, Seaman S, et al. (2005). "Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R". Cancer Res. 64 (23): 8507–11. doi:10.1158/0008-5472.CAN-04-2716. PMID 15574754. S2CID 1990083.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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