MIR1282

MIR1282
Identifiers
Aliases	MIR1282, MIRN1282, hsa-mir-1282, microRNA 1282
External IDs	GeneCards: MIR1282; OMA:MIR1282 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q15.3 Start 43,793,659 bp[1] End 43,793,759 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve olfactory zone of nasal mucosa gastrocnemius muscle blood dorsolateral prefrontal cortex Achilles tendon heart upper lobe of left lung left ventricle left lobe of thyroid gland n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 100302254 n/a Ensembl ENSG00000221792 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 15: 43.79 – 43.79 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

MicroRNA 1282 is a protein that in humans is encoded by the MIR1282 gene. ^[3]

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.