HMBOX1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2CUF, 4J19 |
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Identifiers |
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Aliases | HMBOX1, HNF1LA, HOT1, PBHNF, homeobox containing 1, TAH1 |
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External IDs | MGI: 2445066; HomoloGene: 11589; GeneCards: HMBOX1; OMA:HMBOX1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 8 (human)[1] |
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| Band | 8p21.1-p12 | Start | 28,890,395 bp[1] |
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End | 29,064,764 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 14 (mouse)[2] |
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| Band | 14|14 D1 | Start | 65,049,049 bp[2] |
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End | 65,187,320 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - epithelium of colon
- spinal ganglia
- right adrenal cortex
- olfactory bulb
- secondary oocyte
- cardia
- left adrenal cortex
- pars reticulata
- ventral tegmental area
- trigeminal ganglion
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| Top expressed in | - genital tubercle
- neural layer of retina
- superior frontal gyrus
- ventricular zone
- tail of embryo
- Rostral migratory stream
- dentate gyrus of hippocampal formation granule cell
- gastrula
- cerebellar cortex
- lumbar spinal ganglion
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - DNA binding
- telomerase activity
- double-stranded telomeric DNA binding
- protein binding
- identical protein binding
- telomeric DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- sequence-specific DNA binding
- protein-containing complex binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
| Cellular component | - cytoplasm
- nucleus
- telomerase holoenzyme complex
- nucleoplasm
- cytosol
- nuclear body
- telomere
- chromosome
- Cajal body
- PML body
| Biological process | - positive regulation of transcription, DNA-templated
- positive regulation of telomere maintenance via telomerase
- negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- positive regulation of telomerase activity
- transcription, DNA-templated
- RNA-dependent DNA biosynthetic process
- positive regulation of chromatin binding
- negative regulation of transcription by RNA polymerase II
- regulation of telomerase activity
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001135726 NM_024567 NM_001324382 NM_001324383 NM_001324384
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NM_001324385 NM_001324386 NM_001324387 NM_001324388 NM_001324389 NM_001324390 NM_001324391 NM_001324392 NM_001324393 NM_001324394 NM_001324395 NM_001330498 |
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NM_177338 NM_001347626 NM_001347627 |
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RefSeq (protein) | NP_001129198 NP_001311311 NP_001311312 NP_001311313 NP_001311314
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NP_001311315 NP_001311316 NP_001311317 NP_001311318 NP_001311319 NP_001311320 NP_001311321 NP_001311322 NP_001311323 NP_001311324 NP_001317427 NP_078843 |
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NP_001334555 NP_001334556 NP_796312 |
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Location (UCSC) | Chr 8: 28.89 – 29.06 Mb | Chr 14: 65.05 – 65.19 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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