GHRLOS |
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Identifiers |
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Aliases | GHRLOS, GHRL-AS1, GHRLAS, NCRNA00068, ghrelin opposite strand/antisense RNA |
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External IDs | OMIM: 618445; GeneCards: GHRLOS; OMA:GHRLOS - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 3 (human)[1] |
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| Band | 3p25.3 | Start | 10,285,754 bp[1] |
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End | 10,294,903 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - testicle
- bone marrow cells
- tendon of biceps brachii
- pancreatic ductal cell
- sural nerve
- granulocyte
- body of stomach
- monocyte
- apex of heart
- blood
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| | More reference expression data |
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BioGPS | |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 10.29 – 10.29 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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In molecular biology, ghrelin opposite strand (non-protein coding), also known as GHRLOS, is a long non-coding RNA. It is antisense to the GHRL gene, which encodes ghrelin. In humans, it is located on chromosome 3p25. It is alternatively spliced into multiple isoforms.[3][4]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000240288 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Seim I, Collet C, Herington AC, Chopin LK (2007). "Revised genomic structure of the human ghrelin gene and identification of novel exons, alternative splice variants and natural antisense transcripts". BMC Genomics. 8: 298. doi:10.1186/1471-2164-8-298. PMC 2014779. PMID 17727735.
- ^ Seim I, Carter SL, Herington AC, Chopin LK (2008). "Complex organisation and structure of the ghrelin antisense strand gene GHRLOS, a candidate non-coding RNA gene". BMC Mol Biol. 9: 95. doi:10.1186/1471-2199-9-95. PMC 2621237. PMID 18954468.