Dextranomer
Chemical compound
- D03AX02 (WHO)
- Dextran, 2,3-dihydroxypropyl 2-hydroxy-1,3-propanediyl ethers
- 56087-11-7
N
- 214362
- none
- 30KXI0TVD3
N
Y (what is this?) (verify)Dextranomer (trade name Debrisan, Exudex[1]) is a cicatrizant used in dressings for wound healing,[2] and in pharmaceutical products to treat fecal incontinence.[3] It consists of dextran polymer chains cross-linked into a three-dimensional network.[4]
Solesta
Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI).[5] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).
References
- ^ "Establishment Registration & Device Listing".
- ^ Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med. 31 (1): 28–33. PMID 2413198.
- ^ "Solesta Gel Approved for Fecal Incontinence - Drugs.com MedNews".
- ^ Solesta Package Insert
- ^ Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence". Drugs. 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415. S2CID 6499631.
External links
- dextranomer at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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Preparations for treatment of wounds and ulcers (D03)
- epichlorohydrin: Cadexomer iodine
- Crilanomer
- Dextranomer
- Bromelain (anacaulase)
- Clostridiopeptidase
- Trypsin
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