Butoconazole

Chemical compound
  • US DailyMed: Butoconazole
Pregnancy
category
  • AU: B3
Routes of
administrationVaginal creamATC code
  • G01AF15 (WHO)
Legal statusLegal status
  • US: OTC / Rx-only
Identifiers
  • (RS)-1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole
CAS Number
  • 64872-76-0 checkY
  • 64872-77-1
PubChem CID
  • 47472
DrugBank
  • DB00639 checkY
ChemSpider
  • 43192 checkY
UNII
  • 0Q771797PH
KEGG
  • D00880 ☒N
ChEBI
  • CHEBI:3240 checkY
ChEMBL
  • ChEMBL1295 checkY
CompTox Dashboard (EPA)
  • DTXSID2048537 Edit this at Wikidata
Chemical and physical dataFormulaC19H17Cl3N2SMolar mass411.77 g·mol−13D model (JSmol)
  • Interactive image
  • Clc1ccc(cc1)CCC(Sc2c(Cl)cccc2Cl)Cn3ccnc3
InChI
  • InChI=1S/C19H17Cl3N2S/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22/h1-5,7-8,10-11,13,16H,6,9,12H2 checkY
  • Key:SWLMUYACZKCSHZ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Butoconazole (trade names Gynazole-1, Mycelex-3) is an imidazole antifungal used in gynecology. It is administered as a vaginal cream.[1][2]

References

  1. ^ Seidman LS, Skokos CK (December 2005). "An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis". Infectious Diseases in Obstetrics and Gynecology. 13 (4): 197–206. doi:10.1155/2005/453239. PMC 1784583. PMID 16338779.
  2. ^ Butoconazole Monograph

External links

  • "Butoconazole". Drug Information Portal. U.S. National Library of Medicine.
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