5,6-Dibromotryptamine

Chemical compound

5,6-Dibromotryptamine
Identifiers

IUPAC name 2-(5,6-dibromo-1H-indol-3-yl)ethanamine
PubChem CID	309209
ChemSpider	273389
UNII	QTA0HT8VX3
ChEMBL	ChEMBL256339
CompTox Dashboard (EPA)	DTXSID90309236
Chemical and physical data
Formula	C₁₀H₁₀Br₂N₂
Molar mass	318.012 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1=C2C(=CC(=C1Br)Br)NC=C2CCN
InChI InChI=1S/C10H10Br2N2/c11-8-3-7-6(1-2-13)5-14-10(7)4-9(8)12/h3-5,14H,1-2,13H2 Key:QCSXERFQDJZYFJ-UHFFFAOYSA-N

5,6-Dibromotryptamine is a substituted tryptamine and indolic alkaloid found in some marine sponges such as Hyrtios sp. found in the South Pacific area. 5,6-Dibromotryptamine is potentially an anti bacterial and anti cancer agent.^[1]^[2]

References

^ Mollica A, Locatelli M, Stefanucci A, Pinnen F (May 2012). "Synthesis and bioactivity of secondary metabolites from marine sponges containing dibrominated indolic systems". Molecules. 17 (5). MDPI AG: 6083–6099. doi:10.3390/molecules17056083. PMC 6268355. PMID 22614862.
^ Miguel-Gordo M, Gegunde S, Calabro K, Jennings LK, Alfonso A, Genta-Jouve G, et al. (May 2019). "Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra". Marine Drugs. 17 (6). MDPI AG: 319. doi:10.3390/md17060319. PMC 6627171. PMID 31151240.